2025 College Football Playoff National Championship picks, predictions: Proven expert reveals best bets
The College Football Playoff expanded from four teams to 12 this season and now an exciting postseason will culminate with the 2025 College Football Playoff National Championship Game on Monday. Ohio State cruised to victories of 14 points or more over Tennessee, Oregon and Texas to make the title game while Notre Dame beat Indiana, Georgia and Penn State on its path. Now, the college football powerhouses will go head-to-head with a chance at history on the line after playing each other in the regular season the previous two years.
The latest college odds via SportsLine consensus list Ohio State as 9-point favorites against Notre Dame while the over/under is currently listed at 45.5 (see college football odds here). Ohio State is the -408 favorite (risk $408 to win $100) on the money line, while Notre Dame is +315 (risk $100 to win $315).
Before making any College Football Playoff picks, be sure to check out the college football predictions from our proven CFB expert Thomas Casale.
A frequent guest on national radio and TV shows to discuss college sports, Casale has been betting -- and winning -- for more than 30 years.
Over the past two college football seasons, Casale is 122-92-5 (57%) overall and 26-8 (76.4%) in bowl games -- all publicly documented. He backed the Notre Dame (-2) to cover against Penn State and is now 14-7 in this column dating back to Week 13! Anybody following could have seen STRONG returns.
Now, he's turned his attention to the 2025 College Football Playoff National Championship (see the latest college football lines for each game this week on our college football odds page) and is revealing his top two plays -- including a decisive pick against the spread. You ABSOLUTELY need to see what he's playing before locking in any college football picks.
What are Casale's best bets for the College Football Playoff National Championship Game, and which lines should you jump on now? ... Join SportsLine right now to see Thomas Casale's best bets, all from one of the top college football handicappers in the nation who is on a 14-7 roll in his best bets column!
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