2022 NCAA Tournament Memphis vs. Gonzaga line, picks: Advanced computer college basketball model releases selections for second round matchup

Two of the most talented teams in the country face off when the No. 1 seed Gonzaga Bulldogs take on the No. 9 seed Memphis Tigers at 9:40 p.m. ET on Saturday. Gonzaga is favored by 9.5 points at Caesars Sportsbook, while the Over-Under is set at 155 (see up-to-date odds for every game this week on our college basketball odds page). 

Before making any Memphis vs. Gonzaga picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,500 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Memphis is in the top 50 in the country on both offense and defense. Led by Jalen Duren, the Tigers are in the top five of the country in offensive rebounding and in the top 20 of the nation in free-throw creation rate. Memphis also ranks in the top 25 in assist rate this season, with above-average marks in 3-point shooting and 2-point shooting. The Tigers also face a Gonzaga defense that ranks below the national average in turnover creation rate and steal rate this season.

The model also knows Gonzaga has the nation's best offense. The Bulldogs are leading the country in adjusted offensive efficiency, and Gonzaga is making more than 60 percent of 2-point attempts this season. The Bulldogs are also in the top 20 in 3-point shooting, and Gonzaga has talent at every level. Gonzaga also commits a turnover on only 15.7 percent of offensive possessions while securing more than 29 percent of missed shots on the offensive glass.

Now, it has set its sights on Memphis vs. Gonzaga. We can tell you the model is leaning under the total, and it also says one side of the spread hits in 70 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Memphis vs. Gonzaga? And which side of the spread hits in 70 percent of simulations? ... Join SportsLine right now to find out which side of the Memphis vs. Gonzaga spread you should be all over Saturday, all from the model on a roll on college basketball picks!