Detroit +6 DET +6 Detroit 27 @ San Francisco 30 9/16 DET 27 @ SF 30 9/16 WIN Sun 9/16 This line SCREAMS overreaction. I get it, losing to a Jets rookie 48-17 should raise some flags but Matt Stafford and the Lions do not deserve to be this large of an underdog Week 2. One of my favorite ways to gauge a bet in the NFL is looking at the line flipped for home field. This line states that the Lions would essentially be EVEN at home against a 49ers team that finished last in the NFC West a season ago. Until Jimmy G and the 49ers earn a win, I am not ready to tail them against a proven offense. Pile on the Lions here and even consider sprinkling a unit on the money line at +225.