Bills vs Saints prediction, props, odds: Top NFL expert reveals player prop bet picks for Thanksgiving game

The New Orleans Saints (5-5) host Josh Allen and the Buffalo Bills (6-4) in the final game of the 2021 NFL Thanksgiving schedule for a key Week 12 game between two teams in the thick of playoff races. Kickoff is at 8:20 p.m. ET. The Bills are favored by six points in the latest Bills vs Saints odds from Caesars Sportsbook, and the over-under is set at 45.5 points. In addition to the Saints vs. Bills point spread and NFL Week 12 betting lines, Caesars is also offering a plethora of prop bet options for this Thanksgiving night matchup, and SportsLine NFL expert R.J. White has just revealed his top plays.

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White, a CBS Sports fantasy and gambling editor, ended the 2020 season on an 80-59 run on all NFL picks, returning more than $1,400 during that span. He also enters Week 12 as SportsLine's No. 5 rated NFL expert, going 55-44-2 (+800) on his last 101 NFL ATS picks. It's no surprise, as White has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest. Anyone who has followed his picks has seen HUGE returns.

You can see all of White's expert NFL picks and analysis HERE.

Now, White has locked in on Saints vs. Bills and just revealed his top three prop bet picks for this Week 12 NFL Thanksgiving matchup.

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Zack Moss Under 21.5 rushing yards (-125)

"Twelve weeks into the season, Matt Brieda is becoming a thing in the Bills offense. The veteran running back saw a season-high 32% of the snap count on offense last week, and there are indications that could continue to grow. Moss has done virtually nothing since the bye as the Bills offense has struggled. Throw out his 27 yards on seven carries in the blowout win over the Jets and he's managed only 30 yards on 14 carries, barely topping two yards per carry. He had just three carries on either side of that Jets game, and unless things have drastically changed in the last few days, we shouldn't expect much of a workload here. The Unders on both Moss and Devin Singletary look appealing, but Moss in particular figures to be a longshot to see the number of carries it would take to reach his rushing yardage number."

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Josh Allen Under 274.5 passing yards (-115)

"The Bills offense hasn't looked right since the bye aside from pasting an awful Jets defense. In the other three games they've played since the break, Allen hasn't hit this yardage total once. Buffalo scored 26 against Miami but 10 came at the end of the game and the offense wasn't otherwise impressive. The next week, the Bills faceplanted against the Jaguars, scoring just six points. And last week, four turnovers led to a blowout loss. The Saints have held two straight opponents under 200 net passing yards. This game isn't expected to be a shootout like Allen's last two 300-yard games with the Saints dealing with significant injuries on the offensive side, so I can't see the Bills quarterback posting a massive game through the air."

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Matt Breida Anytime TD (+440) and First TD (+2600)

"Speaking of Breida, the former 49ers and Dolphins back scored two touchdowns against the Jets despite playing just eight snaps on offense. The team rewarded that nose for the end zone by giving him 18 snaps against the Colts, which was two more than Zack Moss and just three less than Devin Singletary. But Breida did the most with his workload, rushing for 51 yards on five carries and recording a 16-yard reception. He got the most work inside the 10-yard line last week as well, and he figures to be an option for touches if the Bills are close to the goal line this week. The anytime touchdown prop seems to be great value considering his growing role, and the first TD prop is worth a sprinkle at this longshot price as well."

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