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Yankees vs. Tigers line, odds, start time, pick, best bets for April 7 matchup from proven model

SportsLine's projection model, which is on a profitable 34-19 run, has locked in its MLB picks for the New York Yankees vs. Detroit Tigers at Comerica Park on Monday

By@SportsLinePublished: Apr 07, 2025 5:13PM UTC . 2 min read

The New York Yankees and Detroit Tigers are set to begin a three-game series in Detroit on Monday, with the Yankees off to a 6-3 start and the Tigers at 5-4 through nine games. New York had its three-game winning streak snapped in a 5-4 loss to the Pirates in 11 innings on Sunday. Detroit enters on a three-game winning streak and is 5-1 since being swept by the Dodgers to begin its season. 

First pitch from Comerica Park in Detroit, Mich., is set for 3:10 p.m. ET. New York is a -157 favorite on the money line (risk $157 to win $100) in the latest Yankees vs. Tigers odds, while Detroit is a +133 underdog. The over/under is 8.5 in the latest MLB odds via SportsLine consensus.

Before making any Yankees vs. Tigers picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 2 of the 2025 MLB season on a 34-19 roll on top-rated run-line picks (+629). Anybody following could have seen strong returns!

The model has simulated Yankees vs. Tigers 10,000 times and the results are in. We can tell you the model is leaning Over on the run total, and it also says one side of the money line is the better value!

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