Yankees vs. Guardians odds, line, prediction: 2026 MLB picks for Wednesday, June 10 from proven model

The New York Yankees (40-26) will look to complete a three-game sweep when they visit the Cleveland Guardians (37-32) for the series finale on Wednesday. New York has won both games of the series, including a 7-5 extra-innings win on Monday and a 3-2 win on Tuesday, and the Yankees have won six of their last seven games overall. Parker Messick (6-2, 2.40 ERA) will start for Cleveland, while Carlos Rodon (1-2, 2.88 ERA) will take the ball for New York. The Yankees lead the season series 3-2 in 2026.

First pitch is set for 1:10 p.m. ET from Progressive Field in Cleveland. Cleveland is the -119 favorite on the money line (risk $119 to win $100) in the latest Yankees vs. Guardians odds. The over/under for total runs is 7.5.

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