Virginia Tech has won 16 of its last 17 games against Virginia, and bragging rights are back on the line this weekend in the Commonwealth Clash. By now, it's a foregone conclusion that Pitt will win the ACC Coastal division, but both teams would be happy to end the regular season with a win on Saturday. Virginia has lost its last three games, while the Hokies have alternated wins and losses for the last five weeks. 

Kickoff is set for 3:45 p.m. ET from David A. Harrison III Field at Scott Stadium, where the Cavaliers are 7-1 against the spread as a home favorite in their last eight games. The Cavaliers are favored by seven points in the latest Virginia vs. Virginia Tech odds from Caesars Sportsbook, and the over-under is set at 62.5. Before you make any Virginia Tech vs. Virginia picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 13 of the 2021 season on a 39-25 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Virginia vs. Virginia Tech 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins Virginia vs. Virginia Tech? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks ... If you're already a member, see the picks below!