Virginia vs. Duke odds, line: 2025 ACC Championship Game picks from proven model
SportsLine's model has locked in its best bets for the 2025 ACC title game between Duke and Virginia on Saturday
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The Duke Blue Devils and Virginia Cavaliers square off in the 2025 ACC Championship Game in Charlotte on Saturday. Duke is 7-5 overall this season, but went 6-2 in the ACC and won the tiebreaker with four other teams. No. 18 Virginia, meanwhile, went 10-2 and had the top record in ACC play at 7-1. The Cavaliers are projected to make the College Football Playoff field with a win in this game.
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Kickoff is at 8 p.m. ET. The Cavaliers are 4-point favorites in the latest Virginia vs. Duke odds, while the over/under is 58.5.
Before making any Virginia vs. Duke picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.
The model simulates every FBS game 10,000 times, and it is profitable on its top-rated money-line and over/under picks since the beginning of the 2024 season. Anyone following could have seen impressive returns.
The model has simulated this matchup 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits in nearly 60% of simulations!
So who wins Duke vs. Virginia, and which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!
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