The No. 19 Connecticut Huskies will try to extend their two-game winning streak when they host the No. 12 St. John's Red Storm on Friday night. UConn beat DePaul by double digits at home last Wednesday before going on the road and taking down then-No. 9 Marquette on Saturday. St. John's is riding a nine-game winning streak and is one game ahead of Creighton for first place in the Big East standings.  

Tipoff is set for 8 p.m. ET on Friday at Harry A. Gampel Pavilion. UConn is favored by 3.5 points in the latest UConn vs. St. John's odds, while the over/under is 141.5 points, per SportsLine consensus. 

Before entering any St. John's vs. UConn picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 14 of the 2024-25 season on a 208-149 betting roll (+2275) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has simulated UConn vs. St. John's 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in nearly 70% of simulations! 

So who wins UConn vs. St. John's? And which side of the spread hits nearly 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!