The Minnesota Twins (52-60) and the Detroit Tigers (66-48) play in a divisional matchup on Tuesday. Detroit took the first game with a 6-3 win over Minnesota. Zebby Matthews (2-3, 5.67 ERA) takes the ball for the Twins as they look to bounce back. Chris Paddack (4-9, 4.77 ERA) will counter for the Tigers.
First pitch is scheduled for 6:40 p.m. ET at Comerica Park in Detroit. The Tigers are the -153 money-line favorites (risk $153 to win $100) in the latest Twins vs. Tigers odds, while the Twins are +127 underdogs (risk $100 to win $127). The over/under for total runs scored is 8 in the latest MLB odds.
Before you make any Twins vs. Tigers picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.
The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 20 of the 2025 MLB season a profitable 28-23 on top-rated MLB money-line picks. It has excelled making home run prop picks this season, returning nearly 60 units of profit. Anybody following could have seen strong returns!
The model has simulated Twins vs. Tigers 10,000 times and the results are in. We can tell you the model is going Over on the run total, and it also says one side of the money line has all the value!
Who wins Twins vs. Tigers, and which side of the money line has all the value? ... Join SportsLine right now to find out which side of the money line you should be all over, all from the model on a 28-23 roll on top-rated MLB money-line picks!
GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!
Written by Richard Louis
View expert profile
