Timberwolves vs. Nuggets odds, line: Proven model reveals picks for NBA first round Game 5 matchup on Monday, April 27

The sixth-seeded Minnesota Timberwolves look to finish off the third-seeded Denver Nuggets in Game 5 of their Western Conference first-round playoff matchup on Monday. Minnesota took a commanding 3-1 series lead by beating Denver on Saturday, 112-96. Ayo Dosunmo led the Timberwolves with 43 points, while Jamal Murray led the Nuggets with 30. Anthony Edwards (knee) is expected to miss multiple weeks for the Timberwolves. The Timberwolves also lost Donte DiVincenzo for the season with a torn Achilles. 

Tip-off from Ball Arena in Denver is set for 10:30 p.m. ET. The Timberwolves lead the all-time postseason series 12-9, and have won two out of three of the playoff series with the Nuggets. The Nuggets are a 10.5-point favorite in the latest Timberwolves vs. Nuggets odds from FanDuel Sportsbook, while the over/under for total points scored is 222.5. 

Before making any Timberwolves vs. Nuggets picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered the first full week of the 2026 NBA playoffs on a sizzling 24-9 roll (73%) on top-rated NBA spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Nuggets vs. Timberwolves 10,000 times and the results are in. The model is going Over on the point total, and it also says one side of the spread hits 60% of the time!

Who wins Timberwolves vs. Nuggets, and which side of the spread hits 60% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 24-9 roll on top-rated NBA picks!