The Chicago White Sox will look to clinch the series win when they battle the Detroit Tigers in the second of a three-game set between American League Central rivals on Saturday. Chicago earned a 4-3 win in 10 innings on Friday night. The Tigers (22-36), who have lost two in a row, are 8-22 on the road this season. The White Sox (30-27), who have won three in a row, are 18-11 on their home field in 2026.
First pitch from Guaranteed Rate Field in Chicago is set for 2:10 p.m. ET. The Tigers lead the all-time series 1,145-1,115, and have won eight of the last 14 meetings. Detroit is a -136 favorite on the money line (risk $136 to win $100) in the latest Tigers vs. White Sox odds, while the over/under, is 8.