Tigers vs. White Sox odds, line, prediction: 2026 MLB picks for Saturday, May 30, from proven model

The Chicago White Sox will look to clinch the series win when they battle the Detroit Tigers in the second of a three-game set between American League Central rivals on Saturday. Chicago earned a 4-3 win in 10 innings on Friday night. The Tigers (22-36), who have lost two in a row, are 8-22 on the road this season. The White Sox (30-27), who have won three in a row, are 18-11 on their home field in 2026.

First pitch from Guaranteed Rate Field in Chicago is set for 2:10 p.m. ET. The Tigers lead the all-time series 1,145-1,115, and have won eight of the last 14 meetings. Detroit is a -136 favorite on the money line (risk $136 to win $100) in the latest Tigers vs. White Sox odds, while the over/under, is 8. 

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The model has simulated Tigers vs. White Sox 10,000 times and the results are in. The model is going Over on the total, and is also says one side of the money line has ALL the value!

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