Suns vs. Thunder odds, line: Proven model reveals picks for NBA first round Game 2 matchup on Wednesday, April 22

The top-seeded Oklahoma City Thunder will look to take a commanding 2-0 series lead against the eighth-seeded Phoenix Suns when they meet in Game 2 of their Western Conference first-round matchup on Wednesday. Oklahoma City clobbered Phoenix 119-84 in the series opener on Sunday. The Suns (46-39), who have lost three of their last five games, are 20-21 on the road this season. The Thunder (65-18), who have won three of their last five games, are 34-7 on their home court this season.

Tip-off from the Paycom Center in Oklahoma City is set for 9:30 p.m. ET. The Suns lead the all-time series 138-126, but in the postseason, the teams are 13-13. The Pistons are a 17.5-point favorite in the latest Suns vs. Thunder odds from FanDuel Sportsbook, while the over/under for total points scored is 214.5. 

Before making any Thunder vs. Suns picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered the first full week of the 2026 NBA playoffs on a sizzling 24-9 roll (73%) on top-rated NBA spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Suns vs. Thunder 10,000 times and the results are in. The model is going Under on the point total, and it also says one side of the spread hits well over 60% of the time!

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