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Stanford vs. Notre Dame odds, line, spread: Proven model reveals college football picks, predictions for Week 13, 2021

SportsLine's advanced model simulated Notre Dame vs. Stanford and released its 2021 CFB picks and best bets
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The Legends Trophy is on the line on Saturday night when the Stanford Cardinal and Notre Dame Fighting Irish square off for the 24th consecutive year. Things haven't gone the Cardinal's way this season since it beat Oregon, which was ranked third in the nation at the time, all the way back on October 2. Stanford has lost six straight games, but have a great chance to play spoiler to Notre Dame, which is hoping to squeeze its way in the final College Football Playoff rankings.

This year's matchup is set to go off at Stanford Stadium at 8 p.m. ET, where the Cardinal is just 1-3 against the spread as a double-digit underdog since 2019. The Fighting Irish are favored by 19 points in the latest Stanford vs. Notre Dame odds from Caesars Sportsbook, and the over-under is set at 52.5. Before you make any Notre Dame vs. Stanford picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 13 of the 2021 season on a 39-25 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Stanford vs. Notre Dame 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it's also generated a point-spread pick that is hitting in nearly 60 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins Stanford vs. Notre Dame? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks ... If you're already a member, see the picks below!

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SportsLine Staff