The No. 22 St. John's Red Storm will continue their season-opening four-game homestand when they host the Wagner Seahawks on Wednesday night. St. John's has cruised to a pair of blowout wins over Fordham and Quinnipiac to jump into the top 25 for the first time since 2019. Wagner is facing its second ranked opponent after losing to then-No. 25 Rutgers in its season opener last week.  

Tipoff is set for 6:30 p.m. ET on Wednesday at Carnesecca Arena. St. John's is favored by 24 points in the latest St. John's vs. Wagner odds, while the over/under is 144 points, per SportsLine consensus. Before entering any Wagner vs. St. John's picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 2 of the 2024-25 season on a 155-110 betting roll (+2102) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps has seen HUGE returns!

The model has simulated St. John's vs. Wagner 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 60% of simulations. You can only see the pick at SportsLine.

So who wins St. John's vs. Wagner? And which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.