Spurs vs. Trail Blazers odds, line: Proven model reveals picks for NBA first round Game 4 matchup on Sunday, April 26

The seventh-seeded Portland Trail Blazers will look to draw even in their best-of-seven series when they battle the visiting second-seeded San Antonio Spurs in Game 4 of their Western Conference first-round playoff matchup on Sunday. San Antonio retook control of the series with a 120-108 win at Portland on Friday to grab a 2-1 series lead. The Spurs (62-20), who won the Southwest Division, are 30-12 on the road this season, including the postseason. The Trail Blazers (42-40), who finished fourth in the Northwest Division, are 24-18 on their home court, including the playoffs.

Tip-off from Moda Center at the Rose Quarter in Portland, Ore., is set for 3:30 p.m. ET. The Spurs lead the all-time postseason series 16-7, and have won three of the past four playoff meetings. The Spurs are a 5.5-point favorite in the latest Spurs vs. Trail Blazers odds from FanDuel Sportsbook, while the over/under for total points scored is 218.5. 

Before making any Spurs vs. Trail Blazers picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered the first full week of the 2026 NBA playoffs on a sizzling 24-9 roll (73%) on top-rated NBA spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Spurs vs. Trail Blazers 10,000 times and the results are in. The model is going Over on the point total, and it also says one side of the spread hits nearly 60% of the time!

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