Spurs vs. Blazers odds, line: Proven model reveals Game 3 picks for NBA playoff matchup on Friday, April 24

Game 3 of Spurs vs. Blazers in the first round of the 2026 NBA playoffs is set for Friday after the Spurs dropped one on their home court and the Blazers evened the series 1-1. The Spurs, however, remain the series favorites at FanDuel Sportsbook at -600. Portland hopes to take a commanding 3-1 series lead with the next two games on home court. Victor Wembanyama (concussion protocol) is listed as day-to-day. 

Tipoff is at 10:30 p.m. ET at the Moda Center at the Rose Quarter in Portland. The latest Spurs vs. Blazers odds have San Antonio as a 2.5-point favorite, while the over/under for total points scored is 220.5.

Before making any Blazers vs. Spurs picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered the 2026 NBA playoffs on a sizzling 24-9 roll (73%) on top-rated NBA spread picks. Anyone following could have seen HUGE returns!

The model has simulated Spurs vs. Blazers 10,000 times and the results are in. The model is going Under on the point total, and it also says one side of the spread hits well over 60% of the time!

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