Southern Miss (1-9) and Louisiana Tech (3-7) face off in a Conference USA showdown Friday night on CBS Sports Network. The Golden Eagles have dropped eight straight games. Last week they were defeated 27-17 by UTSA. The Bulldogs snapped their five-game losing streak last week when they beat Charlotte 42-32. 

Kickoff from Joe Aillet Stadium is set for 8 p.m. ET. Louisiana Tech is favored by 15.5 points in the latest Southern Miss vs. Louisiana Tech odds from Caesars Sportsbook, while the Over-Under is set at 48.5 points. 

Before making any Southern Miss vs. Louisiana Tech picks, you'll want to see the college football predictions from the SportsLine Projection Model. 

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 12 of the 2021 season on a 36-23 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Southern Miss vs. Louisiana Tech 10,000 times and the results are in. We can tell you that the model is leaning over the total, and it also says one side of the spread hits in over 60 percent of simulations. You absolutely need to see it before locking in your own picks!

So who wins Southern Miss vs. Louisiana Tech? And which side of the spread hits in over 60 percent of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.