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Royals vs. Yankees odds, line, prediction: 2026 MLB picks for Saturday afternoon from proven model

SportsLine's projection model, which is on a 35-29 roll on top-rated MLB money-line picks, has locked in its MLB picks for Royals vs. Yankees on Saturday

ByUpdated: Apr 18, 2026 2:15AM UTC . 2 min read

The New York Yankees will look to make it two in a row when they take on the Kansas City Royals in the second of their three-game series on Saturday. New York is coming off a 4-2 win over Kansas City on Friday night. The Royals (7-13), who have lost five straight, are 2-8 on the road this season. The Yankees (11-9), who are second in the American League East, are 6-5 on their home field.

First pitch from Yankee Stadium in New York is set for 1:35 p.m. ET. The Yankees lead the all-time series 338-215, including wins in 11 of the last 12 meetings. New York is a -163 favorite on the money line (risk $163 to win $100) in the latest Royals vs. Yankees odds, while the over/under, is 8. 

Before making any Royals vs. Yankees picks, or MLB predictions, you NEED to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It was a profitable 35-29 on top-rated MLB money-line picks last season. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following could have seen strong returns!

The model has simulated Royals vs. Yankees 10,000 times and the results are in. The model is going Over on the total, and is also says one side of the money line has ALL the value!

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Daniel Kohn
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