Rays vs. Yankees odds, line, prediction: 2026 MLB picks for Saturday, May 23, from proven model

The Tampa Bay Rays look to extend their winning streak to six games when they take on the American League East-rival New York Yankees on Saturday afternoon. Tampa Bay defeated New York 4-2 on Friday night. The Rays (34-15), who have not won the AL East title since 2021, are 15-10 on the road this season. The Yankees (30-22), who now trail Tampa Bay by 5.5 games in the division, are 16-9 on their home field in 2026.

First pitch from Yankee Stadium is set for 1:35 p.m. ET. The Yankees lead the all-time series 274-211, and have won five of the last nine meetings. New York is a -133 favorite on the money line (risk $133 to win $100) in the latest Rays vs. Yankees odds, while the over/under, is 7. 

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The model has simulated Rays vs. Yankees 10,000 times and the results are in. The model is going Over on the total, and is also says one side of the money line has ALL the value!

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