Rays vs. Orioles odds, line, prediction: 2026 MLB picks for Monday, May 25, from proven model

The Baltimore Orioles host the Tampa Bay Rays for a Memorial Day matinee to begin a three-game series between the AL East counterparts. The Rays (34-16, 15-11 Away) are bringing a five-game winning streak into Baltimore and are first in the AL East. The Orioles (23-30, 14-13 Home) are currently fourth in the AL East and are coming off a loss to the Detroit Tigers. The Rays are sending Shane McClanahan (5-2, 2.82 ERA, 1.05 WHIP, 47 strikeouts) to the mound, and the Orioles are countering with Kyle Bradish (2-6, 4.13 ERA, 1.51 WHIP, 58 strikeouts).

First pitch from Oriole Park at Camden Yards is set for 1:35 p.m. ET. Tampa Bay is a slight -119 favorite on the money line (risk $119 to win $100) while Baltimore is at -104 in the latest Rays vs. Orioles odds. The over/under for total runs is 7.5. 

Before making any Rays vs. Orioles picks, or MLB predictions, you NEED to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times and enters Week 9 of the MLB season on a sizzling 12-1 run on all top-rated MLB picks. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following could have seen strong returns!   

The model has simulated Rays vs. Orioles 10,000 times and the results are in. The model is going Over on the total, and is also says one side of the money line has ALL the value!

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