A matinee on the Wednesday MLB schedule will see Paul Skenes back on the mound as his Pittsburgh Pirates host the Detroit Tigers. Skenes (9-11, 3.88 ERA) had this start pushed back three days after struggling in recent outings as Pittsburgh (62-66) has split its last 10 games. Detroit will send Jackson Jobe (1-1, 6.23 ERA) to the mound as the righty makes his third start of the year. This is the rubber match after Detroit took Monday's contest, with Pittsburgh then taking Tuesday's matchup.
First pitch is at 12:35 p.m. ET from PNC Park in Pittsburgh. The latest Tigers vs. Pirates odds have Pittsburgh as the -150 favorite on the money line (risk $150 to win $100). The over/under is 8.
Before making any Pirates vs. Tigers picks, or MLB predictions, you NEED to see what the SportsLine Projection Model has to say.
The SportsLine Projection Model simulates every MLB game 10,000 times and entered Week 22 of the MLB season on a sizzling 49-31 run on all top-rated MLB picks. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following could have seen strong returns!
The model has simulated Pirates vs. Tigers 10,000 times and the results are in. The model is going Over on the total, and is also says one side of the money line has ALL the value!
Who wins Tigers vs. Pirates, and which side of the money line has ALL the value? ... Join SportsLine right now to find out which side of the money line you should be all over, all from the model that entered Week 22 of the MLB season on a red-hot 49-31 run!
GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!
Written by Ross Kelly
View expert profile
