The Philadelphia Phillies will battle the Cincinnati Reds in a key National League matchup on Monday night. The Phillies (68-49), who have won three in a row, are 31-28 on the road this season. The Reds (62-57), who have won two straight, are 33-26 on their home field in 2025.
First pitch from Great American Ball Park in Cincinnati is set for 6:10 p.m. ET. The Phillies have won three of the past four meetings with the Reds. Cincinnati is a -124 favorite on the money line (risk $124 to win $100) in the latest Phillies vs. Reds odds from DraftKings Sportsbook, while the total number of runs Vegas thinks will be scored, or the over/under, is 9.5 in the latest MLB odds.
Before you make any Phillies vs. Reds picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.
The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 21 of the 2025 MLB season a profitable 31-23 on top-rated MLB money-line picks. It has excelled making home run prop picks this season, returning nearly 60 units of profit. Anybody following could have seen strong returns!
The model has simulated Phillies vs. Reds 10,000 times and the results are in. We can tell you the model is going Under on the run total, and it also says one side of the money line has all the value!
Who wins Phillies vs. Reds, and which side of the money line has all the value? ... Join SportsLine right now to find out which side of the money line you should be all over, all from the model on a 31-23 roll on top-rated MLB money-line picks!