The Cleveland Guardians will look for the four-game series sweep when they take on the Baltimore Orioles in a key American League matchup on Thursday afternoon. Cleveland is coming off a 3-2 win on Wednesday. The Orioles (44-57), who are fifth in the AL East, are 22-32 on the road this season. The Guardians (51-50), who are second in the AL Central, are 25-24 on their home field in 2025.
First pitch from Progressive Field in Cleveland is set for 1:10 p.m. ET. The Guardians have won five of the last seven meetings with the Orioles in games played in Cleveland, including three in a row. Cleveland is a -115 favorite on the money line (risk $115 to win $100) in the latest Orioles vs. Guardians odds from DraftKings Sportsbook, while the total number of runs Vegas thinks will be scored, or the over-under, is 9 in the latest MLB odds.
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Written by Daniel Kohn
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