An interleague matchup on Tuesday's MLB schedule has the Baltimore Orioles hosting the Arizona Diamondbacks. Baltimore (9-7) has won three in a row and defeated the Dbacks on Monday. Arizona (9-8) is 9-5 since dropping its first three games of the season to the defending champion Dodgers. Merrill Kelly, who was 12-9 with a 3.52 ERA in 2025, will make his first start of the year for Arizona after starting the year on the IL, while Trevor Rogers (2-0, 1.89 ERA) takes the mound for the O's.
First pitch is at 6:35 p.m. ET from Orioles Park at Camden Yards in Baltimore. The latest Diamondbacks vs. Orioles odds list Baltimore as the -163 favorite on the money line (risk $163 to win $100). The over/under for total runs is 8.5.