Two teams looking to end the year on a high note square off Wednesday as the 15th-ranked Oregon Ducks face the North Carolina Tar Heels in the 2022 Holiday Bowl, which returns after a two-year absence due to COVID-19. Oregon (9-3) dropped a 38-34 decision at Oregon State on Nov. 26 for its second loss in three contests after having reeled off eight consecutive victories. North Carolina (9-4) has followed a six-game winning streak with a skid that reached three games with its 39-10 loss to Clemson on Dec. 3 in the ACC championship game.

Kickoff at Petco Park in San Diego is scheduled for 8 p.m. ET. The Ducks are 13-point favorites in the latest Oregon vs. North Carolina odds at Caesars Sportsbook, while the over/under for total points scored is set at 76 (see up-to-date odds for every game this week on our college football odds page). 

Before making any North Carolina vs. Oregon picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows Oregon possesses one of the top offenses in the nation as it ranks fourth in total yards (507.8), 14th in rushing (216.3) and 15th in passing (291.5). The Ducks are ninth in the country in scoring with an average of 39.7 points and have recorded at least 34 in 10 of their last 11 contests. Senior Bo Nix is second with a 71.5 completion percentage and is tied for third among all FBS players with 42 total touchdowns, with his 14 rushing scores the most among all FBS quarterbacks.

The model also knows North Carolina also has a strong offense, ranking 14th in total yards (473.6) and seventh in passing (317.2). Redshirt freshman quarterback Drake Maye has been a force for the Tar Heels with both his arm and his legs. Maye is third in the nation with 4,115 passing yards and sixth with 35 touchdown tosses while leading North Carolina with 653 rushing yards. 

Now, it has set its sights on Oregon vs. North Carolina. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in nearly 70% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Oregon vs. North Carolina in the 2022 Holiday Bowl? And which side of the spread hits in nearly 70% of simulations? ... Join SportsLine right now to find out which side of the North Carolina vs. Oregon spread you should be all over Wednesday, all from the model on a roll on college football picks!