An SEC battle is on tap between the Ole Miss Rebels and the Vanderbilt Commodores at 7:30 p.m. ET on Saturday at Vaught-Hemingway Stadium at Hollingsworth Field. Ole Miss is 8-2 overall and 6-0 at home, while Vanderbilt is 2-8 overall and 1-2 on the road. 

The Rebels are favored by 36.5-points in the latest Ole Miss vs. Vanderbilt odds from Caesars Sportsbook, and the over-under is set at 64.5. Before you make any Vanderbilt vs. Ole Miss picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 12 of the 2021 season on a 36-23 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, it has simulated Ole Miss vs. Vanderbilt 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Ole Miss vs. Vanderbilt? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.