A Big 12 battle is on tap between the Oklahoma Sooners and the No. 25 Iowa State Cyclones at 7 p.m. ET on Wednesday at the Lloyd Noble Center. Oklahoma is 9-4 overall and 5-2 at home, while the Cyclones are 10-2 overall and 0-1 on the road. The Sooners are favored by 3 points in the latest Oklahoma vs. Iowa State odds from Caesars Sportsbook and the over/under is set at 124.5. Before you make any Iowa State vs. Oklahoma picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. The model enters Week 9 of the season 30-16 on all top-rated college basketball picks, returning more than $800 for $100 players. Anybody who has followed it has seen huge returns.

Now, it has simulated Oklahoma vs. Iowa State 10,000 times and the results are in. We can tell you that the model is leaning Over and it's also generated a point-spread pick that is hitting in almost 60% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Oklahoma vs. Iowa State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!