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A Big Ten showdown arrives Saturday as Northwestern makes the trip to Columbus to face No. 20 Ohio State. The Wildcats (6-3) have covered the spread in five of eight games this season, while the Buckeyes (6-3), hosting at the Horseshoe, are looking to get right in front of their home crowd and stay in the Big Ten and College Football Playoff conversation. Both teams will be operating with a backup quarterback as Nicco Marchiol is expected to start in place of Aidan Chiles for Northwestern, while Ohio State continues to roll with freshman Luke Fahey as Julian Sayin remains out indefinitely. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code SPORTSLINE55:
Kickoff is set for noon ET at Ohio Stadium in Columbus. Ohio State is a 14-point favorite, while the over/under is 44.5 in the latest Northwestern vs. Ohio State odds.
Before making any Ohio State vs. Northwestern picks, check out the college football predictions from the SportsLine Projection Model.
The model simulates every FBS game 10,000 times, seeking the best values for spread, money-line and over/under bets.
The model has simulated Ohio State vs. Northwestern 10,000 times and the results are in. The model is going Over on the total, and it also says one side of the spread hits almost 60% of the time!
So who wins Ohio State vs. Northwestern, and which side of the spread hits almost 60% of the time? Join SportsLine right now to see which side of the Northwestern vs. Ohio State spread you need to jump on, all from the computer model that simulates every game 10,000 times!
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