North Texas vs. Charlotte odds, line: 2025 college football picks for Week 9 predictions from proven model

The North Texas Mean Green will look to stay in the American Conference title chase when they battle the Charlotte 49ers in a key matchup on Friday night. North Texas is coming off a 55-17 win over UT-San Antonio, while Charlotte dropped a 49-14 decision to Temple in Week 8. The Mean Green (6-1, 2-1 American), who are tied for fourth in the conference, are 2-0 on the road this season. The 49ers (1-6, 0-4 American), who have lost four in a row, are 1-3 on their home field in 2025.

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month at SportsLine for $1 JOIN NOW. 

Kickoff from Jerry Richardson Stadium in Charlotte, N.C., is at 7 p.m. ET. Charlotte is 2-0 all-time against North Texas. The Mean Green are 25.5-point favorites in the latest North Texas vs. Charlotte odds, while the over/under for total points scored is 61.5 via SportsLine consensus.  

Before making any North Texas vs. Charlotte picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and is a profitable 42-30 combined on money-line and over/under picks since the beginning of 2024. Anyone following at sportsbooks and on betting apps could have seen STRONG returns!

The model has simulated North Texas vs. Charlotte 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in well over 50% of simulations.

So who wins North Texas vs. Charlotte, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month at SportsLine for $1 JOIN NOW.