No. 4 Cincinnati (11-0) and East Carolina (7-4) will face off in an AAC Conference matchup on Friday afternoon. The Bearcats extended their win streak to 11 games after blowing out SMU 48-14. The Pirates won their four straight games after escaping with a 38-35 victory against Navy. 

Kickoff from Dowdy-Ficklen Stadium is set for 3:30 p.m. ET. Cincinnati is favored by 14 points in the latest Cincinnati vs. East Carolina odds from Caesars Sportsbook, while the Over-Under is set at 56.5 points. 

Before making any Cincinnati vs. East Carolina picks, you'll want to see the college football predictions from the SportsLine Projection Model. 

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 13 of the 2021 season on a 39-25 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Cincinnati vs. East Carolina 10,000 times and the results are in. We can tell you that the model is leaning under on the point total, and it also says one side of the spread hits in 60 percent of simulations. You absolutely need to see it before locking in your own picks!

So who wins Cincinnati vs. East Carolina? And which side of the spread hits in 60 percent of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.