Two top national title contenders collide on Friday when the No. 1 Gonzaga Bulldogs and No. 5 Duke Blue Devils square off in a scintillating early season showdown at the T-Mobile Arena in Las Vegas. The Bulldogs (6-0) already have beaten two top five teams in Texas and UCLA. Meanwhile the Blue Devils (6-0) have crushed five overmatched opponents since a season-opening win against No. 10 Kentucky.

Tipoff in this 2021 Continental Tire Challenge matchup is set for 10:30 p.m. ET. The Bulldogs are favored by nine points in the latest Gonzaga vs. Duke odds from Caesars Sportsbook, while the Over/Under for total points scored is 154. (See up-to-date odds for every game this week on our college basketball odds page.) 

Before making any Duke vs. Gonzaga picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Div. I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,100 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows that no team arguably has played better so far this season than Gonzaga. On Nov. 13 the Bulldogs took out No. 5 Texas 86-74. And on Tuesday, they blitzed No. 2 UCLA 83-63 in a game that was never in doubt. So far this season the team is shooting 55.6 percent from the field, which leads the country.

The model also knows that Duke has a do-it-all threat in Wendell Moore Jr. A 6-foot-5 junior from Charlotte, N.C., Moore is the country's only power conference player this season averaging 17 points, six rebounds and five assists and shooting 50.0 percent from the field. He has one of the two triple-doubles in the nation this season and is coming off a 22-point, nine-assist, eight-rebound game against The Citadel.

Now, the model has set its sights on Gonzaga vs. Duke. We can tell you it is leaning Over the total, and it also says one side of the spread has all the value! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Gonzaga vs. Duke? And which side of the spread has all the value? ... Join SportsLine right now to find out which side of the Duke vs. Gonzaga spread you should be all over Friday, all from the model on a roll on college basketball picks!