NFL fans will be treated to four more mouthwatering NFL matchups on Wild Card Weekend. The 2025 NFL playoffs continue on Sunday with three matchups: Broncos vs. Bills (-8.5, 47.5), Packers vs. Eagles (5, 45.5), and Commanders vs. Buccaneers (-3, 50.5), the last of which features this week's highest over/under. The action wraps up on Monday Night Football when the Rams face the Vikings in Arizona after the game was moved from Los Angeles. Minnesota is favored by 2.5 points, according to the latest NFL Wild Card Weekend betting lines, while the over/under is 48.

SportsLine's advanced NFL model has revealed its exact NFL score predictions for every game of NFL Wild Card Weekend, which could mean a huge payday of well over 100-1 if any of them hits. Before you lock in any NFL Wild Card Weekend picks, make sure you see what SportsLine's advanced computer model has to say.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the 2025 NFL playoffs on a 31-14 hot streak on top-rated NFL picks this year -- a stunning 69% success rate. Longer term, it is on a 211-142 roll on top-rated NFL picks that dates back to the 2017 season and a 65-35 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone following could have seen huge returns.

Now, the model has evaluated the latest NFL odds, simulated every snap for NFL Wild Card Weekend, and the results are in.

We can tell you SportsLine's model likes the Buffalo Bills (-8.5, 47.5) to beat the Denver Broncos 30-20. The Bills feature one of the league's most potent offenses. Buffalo enters the 2025 NFL playoffs averaging 30.9 points per game, which ranks second in the NFL. Quarterback Josh Allen has thrown for 3,731 yards, 28 touchdowns and six interceptions this season. He's also racked up 531 rushing yards and 12 rushing touchdowns. The model expects Allen to lead the Bills to victory on Sunday as Buffalo wins in well over 70% of simulations. 

In addition, the model has locked in its exact score prediction for every other NFL playoff game. Nailing these results is key to making profitable NFL Wild Card Weekend picks. You absolutely need to see who to pick before locking in any NFL score predictions.

What are the projected scores for every NFL Wild Card Weekend game? ... Join SportsLine now to get NFL Wild Card Weekend score predictions, all from the model on a dominant 65-35 roll!