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Several uncommon matchups on the Week 7 NFL schedule should provide a little extra appeal to making Week 7 NFL bets. Giants vs. Texans (-9.5) sees New York visiting Houston for the first time in eight years, while Rams vs. Raiders (+5.5) has L.A. traveling to Vegas for the first time ever. Elsewhere, the Chiefs travel to Seattle for the first time since 2018, and the latest Week 7 NFL odds have Seattle as 2.5-point favorites in this potential Super Bowl preview. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code SPORTSLINE55:
The Week 7 NFL odds have a line on the first ever game in Paris, France, as Pittsburgh is favored by 3 points over New Orleans. Slim NFL spreads like that are the norm for this week's slate, with others including Titans vs. Browns (-1.5), Bengals vs. Ravens (-3) and Panthers vs. Buccaneers (+3).
Before locking in any NFL bets, make sure you see what SportsLine's advanced computer model has to say.
The model, which simulates every NFL game 10,000 times, is up more than $5,000 for $100 players on top-rated NFL picks since its inception. The model entered Week 7 of the 2026 NFL season on a 58-48 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!
Now, the model has evaluated the latest NFL odds, simulated every snap for Week 7 of the 2025 NFL season, and the results are in.
We can tell you one of the model's strongest Week 7 NFL picks is that the Jets (-4.5, 38.5) cover versus the Dolphins over 60% of the time in an A-rated pick. Another one of its Week 7 NFL predictions: the Broncos (-4.5, 43.5) cover at the Cardinals at 4:05 p.m. ET. Denver is forecasted to cover the spread in well over 50% of simulations, with the Under hitting over 50% of the time.
The model has also made the call on who wins and covers in every other NFL game this week and identified six projected point totals that are at least a touchdown off the actual O/U, potentially giving you a huge payday with alternate totals! You ABSOLUTELY NEED to see its NFL picks for every game before you make any NFL bets of your own!
So which NFL teams should you back in Week 7, and which six O/U bets should you lock in RIGHT NOW? ... Join SportsLine now to see who wins and covers every single NFL game this week, all from the model on a 58-48 roll on top-rated NFL picks!
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Written by Ross Kelly
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