The NFL season gets underway with all 32 teams in action in Week 1. The defending Super Bowl champion Seattle Seahawks kick things off against the team they beat in the title game, the New England Patriots, when they meet on Wednesday, Sept. 9. The schedule continues the next day when the San Francisco 49ers battle the Los Angeles Rams at Melbourne, Australia.
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There are a number of solid matchups on Kickoff Weekend, including Bills vs. Texans (+1.5), Ravens vs. Colts (+3.5), Bears vs. Panthers (+2.5), Saints vs. Lions (-7), Packers vs. Vikings (-1.5) and Commanders vs. Eagles (-4.5). The Cowboys (-2.5) face the Giants on 'Sunday Night Football' at New York. It will be John Harbaugh's debut as Giants coach.
Before locking in any NFL bets, make sure you see what SportsLine's advanced computer model has to say.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 1 on a 53-37 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!
The model has scoured the Week 1 NFL odds and locked in five confident NFL best bets. If you successfully parlay its sports betting picks, you'd be looking at a massive payout of nearly 23-1.
One pick we'll give away: The model is backing the Over 48.5 combined points in Cowboys vs. Giants to cover nearly 70% of the time.
The model is also backing the Under in a surprising matchup between high-powered offenses! You ABSOLUTELY NEED to see its NFL picks for every game before you make any NFL bets of your own!
So which NFL teams should you back in Week 1, and which five picks should you lock in RIGHT NOW? ... Join SportsLine now to see who wins and covers every single NFL game this week, all from the model on a 53-37 roll on top-rated NFL picks!
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Written by Daniel Kohn
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