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NFL odds, lines, spreads: 2021 Week 6 picks, predictions from proven model

The SportsLine Projection Model, which is up almost $7,900 for $100 players on top-rated NFL picks since its inception, has revealed its Week 6 NFL picks
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Week 6 of the 2021 NFL schedule features several must-see matchups, headlined by Cowboys vs. Patriots. The Cowboys are 3.5-point favorites at Caesars Sportsbook in the latest Week 6 NFL odds. Other top NFL matchups include Chargers vs. Ravens (-3.5) and Cardinals vs. Browns (-2.5).

Before making any NFL picks for Week 6, you NEED to see what the SportsLine Projection Model has to say. 

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 6 of the 2021 season on an incredible 125-83 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

Now, the model has evaluated the latest NFL Vegas odds, simulated every snap for Week 6 of the 2021 NFL season, and the results are in.

We can tell you one of the model's strongest Week 6 NFL picks is that the Broncos (-3.5) cover the spread against the Raiders in well over 50 percent of simulations. Another one of its Week 6 NFL predictions: The Ravens (-3) cover against the Chargers well over 50 percent of the time. The model also says you should back the Under (52) in that game.

The model has also made the call on who will win and cover every other NFL game this week and has identified a Super Bowl contender that goes down HARD! You ABSOLUTELY need to see its NFL picks for every single game before locking in your own.

So which NFL teams should you back this week? And which Super Bowl contender goes down HARD? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned almost $7,900 in profit on top-rated NFL picks!

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SportsLine Staff