NFL odds, lines, spreads: 2021 Week 16 picks, predictions from proven model

The SportsLine Projection Model, which is up over $7,000 for $100 players on top-rated NFL picks since its inception, has revealed its Week 16 NFL picks
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The Week 16 NFL schedule features several must-see matchups, highlighted by Chiefs vs. Steelers. Kansas City is an 8.5-point favorite at Caesars Sportsbook in the latest Week 16 NFL odds. Other top NFL matchups include Ravens vs. Bengals (-3) and Patriots vs. Bills (+2).

Before making any NFL picks for Week 16, you NEED to see what the SportsLine Projection Model has to say. 

The model, which simulates every NFL game 10,000 times, is up over $7,000 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 16 of the 2021 season on an incredible 133-96 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

Now, the model has evaluated the latest NFL Vegas odds, simulated every snap for Week 16 of the 2021 NFL season, and the results are in.

We can tell you one of the model's strongest Week 16 NFL picks is that the Raiders (PK) cover the spread against the Broncos in over 60 percent of simulations. Another one of its Week 16 NFL predictions: The Texans (+10.5) cover against the Chargers well over 50 percent of the time. The model also says you should back the Over (46) in that game.

The model has also made the call on who will win and cover every other NFL game this week and has identified a Super Bowl contender that goes down HARD! You ABSOLUTELY need to see its NFL picks for every single game before locking in your own.

So which NFL teams should you back this week? And which Super Bowl contender goes down HARD? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned over $7,000 on top-rated NFL picks!

SportsLine Staff