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Many bettors are familiar with creating an NFL parlay, but far fewer are well versed with making an NFL longshot parlay. These are high-risk, high-reward predictions often involving multiple legs or plus-money NFL bets if not both. A Week 1 NFL parlay could target alternate lines, exact score predictions, touchdown props and more. Which combination of picks and NFL player props should you consider for a huge payday? Visit our DraftKings promo code review and get $200 in bonus bets as a new user after $5+ in wagers here:
The Texans face the Bills at 1 p.m. ET on Sunday, and Houston has scored exactly 23 points in back-to-back games versus Buffalo. Hitting on the NFL best bet of Houston scoring exactly 23 points again on Sunday carries a +1700 return, as that could be a standalone pick or one parlay leg. Effectively building parlays can pay off big in your NFL betting strategy.
Before making your Week 1 NFL picks and parlays, you NEED to see the Week 1 longshot NFL parlay from SportsLine's proven computer simulation model that could return $1 million for a $10 bettor.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the 2026 NFL season on a 53-37 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!
For Week 1, one of the picks in the six-leg longshot parlay is taking Over 56.5 points on the alternate total (+226) in Cowboys vs. Giants. The model projects 59 combined points.
The parlay also includes other picks from the SportsLine computer model, including multiple touchdown scorer props that return +700 or higher! You ABSOLUTELY need to see these picks before locking in any NFL picks of your own.
What are the top NFL picks for Week 1 that can be combined into a parlay that returns $1 million for $10 bettors? ... Join SportsLine now to see the top NFL picks this week and best bets from SportsLine's proven computer simulation model, and find out!
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Written by Ross Kelly
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