MLB odds, lines, picks, predictions for Tuesday, July 21: 3-way parlay pays over +800

Major League Baseball takes center stage on Tuesday with 15 matchups, many of which will shape the playoff picture and/or have an impact on how teams view themselves for the upcoming trade deadline. 

Among the notable MLB odds for Tuesday include Phillies (-125) against the Dodgers, Yankees (-138) against the Pirates and Braves (-147) against the Padres. 

Before locking in any MLB bets or parlays, make sure you see what SportsLine's advanced computer model has to say. 

The SportsLine Projection Model simulates every MLB game 10,000 times and entered the 2026 MLB All-Star break on a sizzling 33-21 run on all top-rated MLB picks. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following could have seen strong returns!

The model has evaluated the Tuesday MLB odds and locked in three confident MLB best bets. If you successfully parlay them you'd be looking at a big payout of over +800.

One pick we'll give away: The model is backing the Cubs (-119) against the Tigers, saying Chicago wins 63% of the time. 

The model has also locked in a pair of underdog plays, pushing this parlay higher than +800! You ABSOLUTELY need to see it right now.

So what are the MLB best bets for Tuesday? ... Join SportsLine now to see who wins every single MLB game, all from the model that's on a 35-21 run on top-rated MLB picks!

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