MLB odds, lines, picks, predictions for Thursday, Aug. 6: 3-way parlay pays over +500

An abbreviated 11-game schedule highlights Thursday's Major League Baseball action, including an intriguing National League West matchup between the San Diego Padres and Arizona Diamondbacks at 9:40 p.m. ET. Other interesting matchups to consider within an MLB parlay include Pirates vs. Brewers, Blue Jays vs. Cubs and White Sox vs. Red Sox.

Toronto is the -116 road favorite (risk $116 to win $100) over the Cubs per the latest MLB odds as they meet in a makeup game at Wrigley Field in Chicago. The Brewers (-129) are also favored versus the Pirates, with the Red Sox (-190) home favorites against the White Sox.

Before locking in any MLB bets or parlays, make sure you see what SportsLine's advanced computer model has to say. 

The SportsLine Projection Model simulates every MLB game 10,000 times and entered Week 20 of the MLB season on a sizzling 42-29 run on all top-rated MLB picks. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following could have seen strong returns!

The model has evaluated the Thursday MLB odds and locked in three confident MLB best bets. If you successfully parlay them you'd be looking at a big payout of over +500.

One pick we'll give away: The model is backing the Under 9 in the White Sox vs. Red Sox matchup, saying the Under hits well over 50% of the time. 

The model has also locked in two other plays, creating an MLB parlay which pays out over +500! You ABSOLUTELY need to see it right now.

So what are the MLB best bets for Thursday? ... Join SportsLine now to see who wins every single MLB game, all from the model that's on a 42-29 run on top-rated MLB picks!

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