Mariners vs. Tigers odds, line, prediction: 2026 MLB picks for Saturday, June 6, from proven model

Teams looking to stay hot meet when the Seattle Mariners face the Detroit Tigers in Game 2 of their three-game American League series on Saturday afternoon. Detroit earned a 7-3 win over Seattle on Friday. The Mariners (33-31), who have won eight of their past 10 games, are 14-15 on the road this season. The Tigers (26-38), who have won four in a row, are 15-14 on their home field in 2026.

First pitch from Comerica Park in Detroit is set for 1:10 p.m. ET. The Tigers lead the all-time series 237-218, but the Mariners have won seven of the past 10 meetings. Seattle is a -135 favorite on the money line (risk $135 to win $100) in the latest Mariners vs. Tigers odds, while the over/under, is 8.5. 

Before making any Mariners vs. Tigers picks, or MLB predictions, you NEED to see what the SportsLine Projection Model has to say.

SportsLine Projection Model simulates every MLB game 10,000 times and enters Week 11 of the MLB season on a red-hot 17-5 run (77%) on all top-rated MLB picks. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following could have seen strong returns!   

The model has simulated Mariners vs. Tigers 10,000 times and the results are in. The model is going Over on the total, and is also says one side of the money line has ALL the value!

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