The first Sunday Night Baseball game of the 2026 MLB season will see a pair of divisional winners from last year facing off as the Cleveland Guardians visit the Seattle Mariners. Cleveland (2-1) won the AL Central with an 88-74 record before bowing out in the Wild Card Round. Seattle (1-2) clinched the AL West with a 90-72 mark before falling in seven games in the ALCS. Emerson Hancock (4-5, 4.90 ERA) will start for the Mariners, with Slade Cecconi (7-7, 4.30 ERA) going for the Guardians.
First pitch is at 7:20 p.m. ET from T-Mobile Park in Seattle. The latest Guardians vs. Mariners odds list Seattle as the -144 favorite on the money line (risk $144 to win $100), with Cleveland as the +121 underdog (risk $100 to win $121). The over/under for total runs is 7.5.