Magic vs. Pistons odds, line: Proven model reveals picks for NBA first round Game 2 matchup on Wednesday, April 22

The top-seeded Detroit Pistons will look to draw even with the eighth-seeded Orlando Magic when they meet in Game 2 of their Eastern Conference first-round matchup on Wednesday. Orlando stunned Detroit 112-101 in the series opener on Sunday. The Magic (45-37), who have not advanced past the first round since 2009-2010, are 20-20 on the road this season. The Pistons (60-22), who have not advanced to the second round since 2007-2008, are 31-10 on their home court this season.

Tip-off from Little Caesars Arena in Detroit is set for 7 p.m. ET. The Pistons lead the all-time series 85-69, including a 12-8 edge in the postseason. The Pistons are a 9.5-point favorite in the latest Magic vs. Pistons odds from FanDuel Sportsbook, while the over/under for total points scored is 218.5. 

Before making any Magic vs. Pistons picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered the first full week of the 2026 NBA playoffs on a sizzling 24-9 roll (73%) on top-rated NBA spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Magic vs. Pistons 10,000 times and the results are in. The model is going Under on the point total, and it also says one side of the spread hits 60% of the time!

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