The Louisville Cardinals will battle the West Virginia Mountaineers in a Battle 4 Atlantis semifinal matchup on Thanksgiving Day. Louisville advanced with an 89-61 thrashing of 14th-ranked Indiana on Wednesday, while West Virginia rallied for an 86-78 overtime win over third-ranked Gonzaga in their first-round matchup. The Cardinals (4-1), who finished 15th in the Atlantic Coast Conference at 3-17 and were 8-24 overall a year ago, have won three in a row. The Mountaineers (4-1), who tied with Oklahoma State for 13th in the Big 12 at 4-14 and were 9-23 overall in 2023-24, are riding a two-game winning streak.
Tip-off from Imperial Arena at Paradise Island, Bahamas is set for noon ET. The Cardinals are 2.5-point favorites in the latest Louisville vs. West Virginia odds from SportsLine consensus, while the over/under for total points scored is set at 151. Louisville is the -142 money line favorite (risk $142 to win $100), while West Virginia is the +120 underdog. Before entering any Louisville vs. West Virginia picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.
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The model has simulated Louisville vs. West Virginia 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting well over 60% of the time!
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