The Dallas Cowboys and the Detroit Lions are set to square off in an NFC battle that could have postseason implications on Sunday at AT&T Stadium. Dallas is 3-2 overall and 0-2 at home, while Detroit is 3-1 overall and 1-0 on the road. The Cowboys have won two straight and are coming off a 20-17 win over the Pittsburgh Steelers. Detroit is coming off a bye and has also won two straight. In their last outing, the Lions beat the Seattle Seahawks 42-29.

Kickoff is scheduled for 4:25 p.m. ET. The Lions are favored by 3 points in the latest Cowboys vs. Lions odds from SportsLine consensus, and the over/under is 52.5 points. Before locking in any Cowboys vs. Lions picks, you'll want to see the NFL predictions and betting advice from the proven computer simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2024 NFL season on an incredible 10-2 hot streak on top-rated NFL picks this year. Longer term, it is on a 191-131 roll on top-rated NFL picks that dates back to the 2017 season and a 45-23 roll on top-rated NFL picks since Week 7 of 2022. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

The model has simulated Cowboys vs. Lions 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it's also generated a point-spread pick that hits in over 50% of computer simulations!

So who wins Cowboys vs. Lions, and which side of the spread hits in over 50% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks!