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Lions vs. Chiefs line, odds: Proven model releases spread pick for 2025 NFL Week 6 Sunday Night Football

The SportsLine projection model, which is on a 41-21 run on top-rated picks dating back to 2024, reveals its picks for the Detroit Lions vs. Kansas City Chiefs on Sunday Night Football in NFL Week 6

ByPublished: Oct 12, 2025 10:39PM UTC . 2 min read

The Kansas City Chiefs (2-3) will host the Detroit Lions (4-1) on Sunday Night Football in NFL Week 6. The defending AFC champions are off to an inconsistent start this season and are coming off of a 31-28 loss to the Jacksonville Jaguars. They will host a surging Lions team that has won four straight games, most recently topping the Cincinnati Bengals 37-24 in Week 5. 

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Kickoff from Arrowhead Stadium is set for 8:20 p.m. ET. Kansas City is a 2.5-point favorite in the latest Lions vs. Chiefs odds, and the over/under for total points scored is 51.5. The Chiefs are -146 favorites on the money line (risk $146 to win $100), while the Lions are +123 underdogs (risk $100 to win $123).

Before making any Chiefs vs. Lions picks or NFL Week 6 Sunday Night Football predictions of your own, you NEED to see which side the proven SportsLine projection model is on. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 41-21 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

Now, the model has locked in another confident pick for Chiefs vs. Lions on Sunday Night Football in NFL Week 6.

We can tell you it's leaning Under the point total, but also says that one side of the spread hits in well over 50% of simulations! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.

So who wins Lions vs. Chiefs on Sunday Night Football, and which side of the spread hits well over 50% of the time? ... Join SportsLine RIGHT NOW to see which side of the Lions vs. Chiefs line to back, all from the model that has gone 41-21 on top-rated picks since 2024!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW. 

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Chelena Goldman

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