loading...
League Logo
MLB
League Logo
MLB
League Logo
NBA
League Logo
NHL
League Logo
NFL
League Logo
UCL
All
  • Loading...
loading...

Cubs vs. Cardinals odds, line, prediction: Proven MLB model reveals Sunday Night Baseball picks for May 31

SportsLine's projection model, which is on a red-hot 14-4 run on all top-rated MLB picks, has locked in its 'Sunday Night Baseball' predictions for the Chicago Cubs vs. St. Louis Cardinals

ByUpdated: May 31, 2026 1:38PM UTC . 2 min read

One of baseball's classic rivalries will have its next iteration when the Chicago Cubs visit the St. Louis Cardinals on 'Sunday Night Baseball.' These teams have met over 2,500 times in MLB history, with Chicago holding the slight edge in winning 51% of the meetings. The Cubs (32-27) won Saturday's meeting after the Cardinals (30-26) took Friday's opener. Matthew Liberatore (2-3, 4.76 ERA) will start for St. Louis, countered by Chicago's Jordan Wicks (0-1, 16.62 ERA).

First pitch is at 7:20 p.m. ET from Busch Stadium in St. Louis. The latest Cardinals vs. Cubs odds list Chicago as the -116 favorite on the money line (risk $116 to win $100), with St. Louis priced at -104. The over/under for total runs is 8.5.

Before making any Cubs vs. Cardinals picks or MLB predictions, you NEED to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times, and enters Week 10 on a red-hot 14-4 run (78%) on all top-rated MLB picks. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anybody following its MLB betting picks at sportsbooks and on betting sites could have seen strong returns!

The model has simulated Cardinals vs. Cubs 10,000 times and the results are in. The model is going Over on the total, and is also says one side of the money line has ALL the value!

GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!

JOIN NOW
Avatar
Ross Kelly
Share This Story
© 2026 CBS INTERACTIVE INC. ALL RIGHTS RESERVED. SportsLine and SportsLine PRO are registered trademarks of SportsLine.com, Inc.FANS ONLY
In partnership with...247 Sports

FOLLOW US:

The content on this site is for entertainment purposes only and SportsLine makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. There is no gambling offered on this site. This site contains commercial content and SportsLine may be compensated for the links provided on this site.