Cowboys vs. Eagles odds, line: Advanced computer model reveals spread picks for Week 18 game on Saturday

The Dallas Cowboys and Philadelphia Eagles will try to improve their playoff positioning when the NFC East rivals collide in their regular season finale on Saturday night at Lincoln Financial Field in Philadelphia. The Cowboys (11-5) already have clinched the division title and enter the game as the No. 4 seed in the NFC playoff picture. Meanwhile the Eagles (9-7) clinched a spot in the postseason with their win over Washington and Minnesota's loss to Green Bay on Sunday.

Kickoff is 8:15 p.m. ET. Dallas is a 3.5-point favorite in the latest Cowboys vs. Eagles odds from Caesars Sportsbook while the Over/Under for total points scored is 45. (See the latest NFL lines for every game this week on our NFL odds page.)

Before you make any Eagles vs. Cowboys picks, you NEED to check out the latest NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up more than $7,200 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 18 of the 2021 season on an incredible 135-96 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

The model has factored in that Dallas could climb as high as the No. 2 seed in the NFC, so the Cowboys still have a lot to play for. Jerry Jones told media this week that Dallas will play its starters, so Dak Prescott and Co. could build a big lead against a Philadelphia team that might be more cautious with its stars. 

The model also knows that Philadelphia is on a roll. The Eagles have won four straight and six of their last seven games. A key factor in the team's success has been the running game. Over the last four weeks, they have averaged 162.0 rushing yards per game, which ranks second in the NFL in that time, behind only Seattle (177.0).

Now, the model has set its sights on Cowboys vs. Eagles. We can tell you it's leaning Over the total, predicting the teams to score a combined 47 points, and it also says one side of the spread has all the value! You ABSOLUTELY need to see it before locking in any NFL picks of your own.

So who wins Cowboys vs. Eagles on Saturday? And which side of the spread has all the value? ... Join SportsLine right now to find out which side of the Eagles vs. Cowboys spread you should be all over, all from the advanced model that has returned more than $7,200 on top-rated NFL picks!