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College football odds, lines, spreads: Picks, predictions, betting advice for Week 4, 2021 from proven model

The SportsLine Projection Model, which has generated almost $3,000 for $100 college football bettors over the past five-plus years, has revealed its college football picks for Week 4
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The Week 4 college football schedule features a pair of ranked matchups. One is the SEC on CBS game pitting No. 7 Texas A&M and No. 16 Arkansas. The Aggies are six-point favorites, according to Caesars Sportsbook. The other is No. 12 Notre Dame vs. No. 18 Wisconsin (-5.5). 

Before making any college football picks for those games or others in Week 4, be sure to see what the SportsLine Projection Model has to say. 

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. It also enters Week 4 of the 2021 season on a 72-58 run on all top-rated college football picks. Anyone who has followed it has seen HUGE returns.

Now, it has studied the latest college football odds from Caesars (see the latest college football lines for each matchup this week on our college football odds page), simulated every single play for Week 4 of FBS college football, and the results are in. 

One of the college picks the model is high on in Week 4: LSU (-2.5) covers at Mississippi State in a noon ET SEC West kickoff on Saturday. The Tigers cover more than 60 percent of the time, while the over (57) hits with a few points to spare. 

Another prediction: No. 24 UCLA (-6) goes on the road and covers at Stanford in a 6 p.m. ET start in the Pac-12 on Saturday. The simulations show the Bruins covering 60 percent of the time. The over also has substantial value here as it clears in almost 60 percent of simulations. 

The model has also made the call on who wins and covers in every other FBS matchup, and it is calling for a Top 25 favorite to go down HARD. You ABSOLUTELY need to see its college football picks before locking in any of your own. 

So which college football teams should you back this week? And which Top 25 team gets stunned? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned almost $3,000 in profit on top-rated ATS picks over the past five-plus seasons!

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SportsLine Staff