College football odds, lines, spreads: Picks, predictions, betting advice for Week 10, 2022 from proven model

The SportsLine Projection Model, which has generated almost $3,000 for $100 college football bettors over the past six-plus years, has revealed its college football picks for Week 10
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The Week 10 college football schedule features the biggest game so far this season, as No. 3 Georgia will host No. 1 Tennessee in a 3:30 p.m. ET SEC on CBS showdown. The Vols remained unbeaten with their 44-6 win over then-No. 19 Kentucky last week, while Georgia cruised to a win against Florida. Georgia opened as a 10.5-point favorite at Caesars Sportsbook, but the Bulldogs are down to 9-point favorites in the latest Week 10 college football odds. Another game with College Football Playoff implications features No. 6 Alabama at No. 10 LSU (+13.5) on Saturday night. 

Before making any college football picks for those games or others in Week 10, be sure to see what the SportsLine Projection Model has to say.

The SportsLineProjection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.  

Now, it has studied the latest college football odds from Caesars (see the latest college football lines for each matchup this week on our college football odds page), simulated every single play for Week 10 of FBS college football, and the results are in. 

One of the college picks the model is high on in Week 10: No. 4 Clemson (-4) rolls to an easy win at Notre Dame on Saturday night. The Tigers have gone unbeaten through their first eight games, including a trio of wins against ranked opponents. They have had an extra week to prepare for this game, while Notre Dame is coming off a road game at Syracuse. The Fighting Irish have lost three games this season and the model does not expect them to take down Clemson on Saturday.  

Another prediction: Auburn stays within the 12.5-point spread when it travels to Mississippi State on Saturday night. The Tigers are riding a four-game losing streak, but three of those losses have come by two scores. They have had to face a pair of top-10 opponents during that stretch as well, so this will be a more manageable matchup for them. Mississippi State is coming off a pair of double-digit losses to Kentucky and Alabama, which is one reason why the model has Auburn covering this spread almost 70% of the time. 

The model has also made the call on who wins and covers in every other FBS matchup, and its calling for several top-25 teams to go down HARD! 

So which college football teams should you back this week? And which top-25 teams go down HARD? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned almost $3,000 in profit on top-rated ATS picks over the past six-plus seasons!


SportsLine Staff

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